Segmental Bone Reconstruction by Octacalcium Phosphate Collagen Composites with Teriparatide
نویسندگان
چکیده
منابع مشابه
3D Printing of Octacalcium Phosphate Bone Substitutes
Biocompatible calcium phosphate ceramic grafts are able of supporting new bone formation in appropriate environment. The major limitation of these materials usage for medical implants is the absence of accessible methods for their patient-specific fabrication. 3D printing methodology is an excellent approach to overcome the limitation supporting effective and fast fabrication of individual comp...
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It was demonstrated that octacalcium phosphate collagen composite achieved notable bone regeneration in bone defects in preclinical studies. On the basis of the research results, an investigator-initiated exploratory clinical trial was conducted after approval from a local Institutional Review Board. This clinical study was performed as a single-arm non-randomized intervention study. Octacalciu...
متن کاملAn Octacalcium Phosphate Forming Cement
The osteoconductive and possibly osteoinductive characteristics of OCP increased the interest in preparation of bone graft materials that contain OCP in its composition. Calcium phosphate cements (CPCs) were prepared using a mixture of α-tricalcium phosphate (α-TCP) and dicalcium phosphate anhydrous (DCPA), with α-TCP / DCPA molar ratio of 1/1 and distilled water or 0.5 mol / L phosphate aqueou...
متن کاملPolymer Composites for Bone Reconstruction
The need for reconstructive surgery of bones is continuously increasing along with the ageing of the population as well as the increase of traumatologic injuries. In the United States, the number of bone grafts was 350,000 in 2001. Nowadays, over 500,000 bone graft procedures are performed annually, and approximately 2.2 million worldwide (Giannoudis et al., 2005). The estimated cost of these p...
متن کاملHistomorphometric Analysis of Newly-formed Bone Using Octacalcium Phosphate and Bone Matrix Gelatin in Rat Tibial Defects
Background: Repair of bone defects is challenging for reconstructive and orthopedic surgeons. In this study, we aimedto histomorphometrically assess new bone formation in tibial bone defects filled with octacalcium phosphate (OCP),bone matrix gelatin (BMG), and a combination of both.Methods: A total of 96 male Sprague Dawley rats aged 6-8 weeks weighing 120-150 g were randomly allocatedinto thr...
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ژورنال
عنوان ژورنال: Tissue Engineering Part A
سال: 2021
ISSN: 1937-3341,1937-335X
DOI: 10.1089/ten.tea.2020.0150